Relationship Discovery for Drug Recommendation

Medication recommendation systems are designed to deliver personalized drug suggestions that are closely aligned with individual patient needs. Previous studies have primarily concentrated on developing medication embeddings, achieving significant progress. Nonetheless, these approaches often fall short in accurately reflecting individual patient profiles, mainly due to challenges in distinguishing between various patient conditions and the inability to establish precise correlations between specific conditions and appropriate medications. In response to these issues, we introduce DisMed, a model that focuses on patient conditions to enhance personalization. DisMed employs causal inference to discern clear, quantifiable causal links. It then examines patient conditions in depth, recognizing and adapting to the evolving nuances of these conditions, and mapping them directly to corresponding medications. Additionally, DisMed leverages data from multiple patient visits to propose combinations of medications. Comprehensive testing on real-world datasets demonstrates that DisMed not only improves the customization of patient profiles but also surpasses leading models in both precision and safety.