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Learning Module Networks (1212.2517v1)

Published 19 Oct 2012 in cs.LG, cs.CE, and stat.ML

Abstract: Methods for learning Bayesian network structure can discover dependency structure between observed variables, and have been shown to be useful in many applications. However, in domains that involve a large number of variables, the space of possible network structures is enormous, making it difficult, for both computational and statistical reasons, to identify a good model. In this paper, we consider a solution to this problem, suitable for domains where many variables have similar behavior. Our method is based on a new class of models, which we call module networks. A module network explicitly represents the notion of a module - a set of variables that have the same parents in the network and share the same conditional probability distribution. We define the semantics of module networks, and describe an algorithm that learns a module network from data. The algorithm learns both the partitioning of the variables into modules and the dependency structure between the variables. We evaluate our algorithm on synthetic data, and on real data in the domains of gene expression and the stock market. Our results show that module networks generalize better than Bayesian networks, and that the learned module network structure reveals regularities that are obscured in learned Bayesian networks.

Citations (181)

Summary

  • The paper demonstrates how module networks improve model generalization by grouping variables with shared dependencies.
  • It introduces an iterative algorithm that jointly optimizes module assignments and dependency structures, reducing overfitting.
  • Empirical tests on gene expression and stock market data reveal superior performance over traditional Bayesian and clustering methods.

An Overview of Learning Module Networks

The paper by Segal et al. introduces an innovative method designed to enhance the learning of probabilistic graphical models in complex domains characterized by numerous variables that exhibit similar behavior. This method, termed "Module Networks," provides a way to address both computational and statistical challenges that arise when learning Bayesian networks from data with high dimensionality. The core principle of module networks is to partition a large set of variables into modules, where variables within the same module share both parent nodes in the network and conditional probability distributions (CPDs).

The authors propose an algorithm that simultaneously learns the composition of modules and the dependency structure among modules. This algorithm addresses the pitfalls of overfitting in traditional Bayesian networks when faced with limited data by reducing the complexity of the model space and requiring fewer parameters, thus fostering better generalization to unseen datasets. Through evaluations on domains such as gene expression analysis and stock market modeling, module networks demonstrated superior generalization capabilities compared to Bayesian networks.

Framework and Methodology

Module networks comprise two main components: a module network template and a module assignment function. The modules group variables sharing statistical behaviors, each characterized by its set of parents and local probabilistic models. The module assignment function categorizes each variable into these modules based on similar domains.

The learning process employs a structure scoring system derived from Bayesian principles, incorporating priors over possible assignments and structures. This score acts as the posterior probability that integrates over parameter choices, thus quantifying the fit of a model to the observed data. The scoring system further facilitates efficient computation, particularly given that the priors adhere to specific modularity and independence assumptions akin to those used in Bayesian network learning.

Notably, the algorithm iteratively refines both the module assignment and the dependency structures. It employs a heuristic search strategy similar to that in Bayesian networks for optimizing dependency structures while updating module assignments through sequential reassignment, ensuring acyclic module graph structures.

Experimental Results

Through experiments conducted on synthetic, gene expression, and stock market datasets, the researchers demonstrated significant improvements in module networks' ability to generalize from training to test data compared to traditional Bayesian networks. While synthetic datasets facilitated validation against known model structures, gene expression data elucidated biologically plausible module formations, enriched with meaningful annotations when cross-referenced with genomic databases.

In stock market modeling, module networks yielded enriched modules reflective of industrial sectors, demonstrating improved relevance and precision over hierarchical clustering methods such as AutoClass. The logical causative interdependencies discernible among modules offer additional layers of insight into domain behaviors often obscured by detailed Bayesian network structures.

Implications and Future Directions

Module networks present a compelling alternative to standard Bayesian networks in fields marked by high-dimensional data and inherent structure among variable sets. By effectively partitioning the variable space into shared parameter modules, module networks enable robust learning and visualizations of dependency models in complex data environments.

Given the success of module networks in gene expression and stock market data domains, future research directions could focus on enhancing module initialization, adapting the number of modules dynamically, and extending the scalability of algorithms for even larger datasets. Moreover, exploring applicability to other domains or integrating module networks within existing hybrid models could yield additional insights and applications in artificial intelligence and data science.

In summary, Segal et al. contribute a substantial methodological advancement through the introduction of module networks, providing a nuanced approach to learning from data with numerous interrelated and similar-behaving variables. This research underscores the potential for refined scalability and precision in probabilistic modeling, with promising directions for continued advancement.