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Improved Constructions for Non-adaptive Threshold Group Testing

Published 10 Feb 2010 in cs.DM, cs.IT, and math.IT | (1002.2244v3)

Abstract: The basic goal in combinatorial group testing is to identify a set of up to dd defective items within a large population of size n≫dn \gg d using a pooling strategy. Namely, the items can be grouped together in pools, and a single measurement would reveal whether there are one or more defectives in the pool. The threshold model is a generalization of this idea where a measurement returns positive if the number of defectives in the pool reaches a fixed threshold $u &gt; 0$, negative if this number is no more than a fixed lower threshold $\ell &lt; u$, and may behave arbitrarily otherwise. We study non-adaptive threshold group testing (in a possibly noisy setting) and show that, for this problem, O(d<sup>g+2</sup>(log⁡d)log⁡(n/d))O(d<sup>{g+2}</sup> (\log d) \log(n/d)) measurements (where g:=u−ℓ−1g := u-\ell-1 and uu is any fixed constant) suffice to identify the defectives, and also present almost matching lower bounds. This significantly improves the previously known (non-constructive) upper bound O(d<sup>u+1</sup>log⁡(n/d))O(d<sup>{u+1}</sup> \log(n/d)). Moreover, we obtain a framework for explicit construction of measurement schemes using lossless condensers. The number of measurements resulting from this scheme is ideally bounded by O(d<sup>g+3</sup>(log⁡d)log⁡n)O(d<sup>{g+3}</sup> (\log d) \log n). Using state-of-the-art constructions of lossless condensers, however, we obtain explicit testing schemes with O(d<sup>g+3</sup>(log⁡d)qpoly(log⁡n))O(d<sup>{g+3}</sup> (\log d) qpoly(\log n)) and O(d<sup>g+3+β</sup>poly(log⁡n))O(d<sup>{g+3+\beta}</sup> poly(\log n)) measurements, for arbitrary constant $\beta &gt; 0$.

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